منابع مشابه
The Next Therapeutic Challenge in HIV: Polypharmacy
With the adoption of combination antiretroviral therapy (ART), most HIV-infected individuals in care are on five or more medications and at risk of harm from polypharmacy, a risk that likely increases with number of medications, age, and physiologic frailty. Established harms of polypharmacy include decreased medication adherence and increased serious adverse drug events, including organ system...
متن کاملHIV therapy in an ageing population — the challenge of polypharmacy
Pharmacokinetic drug interaction studies performed during the drug development process, or post-licensing provide the substantive data base from which recommendations regarding the use of certain drug combinations are made. However given the sheer number of potential interactions, especially in the context of an ageing population with inevitable co-morbidities and polypharmacy, we need to be ab...
متن کاملPolypharmacy in the HIV-infected older adult population
The prevalence of human immunodeficiency virus (HIV) infection among people older than 50 years is increasing. Older HIV-infected patients are particularly at risk for polypharmacy because they often have multiple comorbidities that require pharmacotherapy. Overall, there is not much known with respect to both the impact of aging on medication use in HIV-infected individuals, and the potential ...
متن کاملPolypharmacy in elderly patients.
BACKGROUND Polypharmacy (ie, the use of multiple medications and/or the administration of more medications than are clinically indicated, representing unnecessary drug use) is common among the elderly. OBJECTIVE The goal of this research was to provide a description of observational studies examining the epidemiology of polypharmacy and to review randomized controlled studies that have been p...
متن کاملPolypharmacy in the Elderly
P roblems related to polypharmacy are most often associated with the elderly. It appears, however, that the number of medications prescribed per se, has only a weak influence on the health of the elderly. The phenomena of adverse drug events are found more frequently in the older population. Such terms as “inappropriate prescribing” or “potentially inappropriate prescriptions” and “adverse reac...
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ژورنال
عنوان ژورنال: Current Opinion in HIV and AIDS
سال: 2020
ISSN: 1746-630X
DOI: 10.1097/coh.0000000000000608